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Showing results for gentisic acid
Search for gentianic acid instead (2 results)
Gentisic acid mitigates gentamicin-induced nephrotoxicity in rats.
Saeedavi M, Goudarzi M, Fatemi I, Basir Z, Noori SMA, Mehrzadi S. Saeedavi M, et al. Tissue Cell. 2023 Oct;84:102191. doi: 10.1016/j.tice.2023.102191. Epub 2023 Aug 1. Tissue Cell. 2023. PMID: 37556917
The current investigation was considered to evaluate the beneficial effects of gentisic acid (GA) on gentamicin (GEN)-induced nephrotoxicity in rat kidneys through assessment of oxidative stress, inflammatory cytokines, and histopathological changes. ...
The current investigation was considered to evaluate the beneficial effects of gentisic acid (GA) on gentamicin (GEN)-induced …
Acetylsalicylic acid and its metabolite gentisic acid may act as adjunctive agents in the treatment of psychiatric disorders.
Altinoz MA, Ozpinar A. Altinoz MA, et al. Behav Pharmacol. 2019 Dec;30(8):627-641. doi: 10.1097/FBP.0000000000000517. Behav Pharmacol. 2019. PMID: 31703028 Review.
In parallel to this new concept, recent investigations indicate that adjunction of acetylsalicylic acid (ASA) to the orthodox psychiatric treatments augments therapeutic efficacy in bipolar disorder and schizophrenia. Gentisic acid is a redox active quinonoid ASA me …
In parallel to this new concept, recent investigations indicate that adjunction of acetylsalicylic acid (ASA) to the orthodox psychiatric tr …
A review on gentisic acid as a plant derived phenolic acid and metabolite of aspirin: Comprehensive pharmacology, toxicology, and some pharmaceutical aspects.
Abedi F, Razavi BM, Hosseinzadeh H. Abedi F, et al. Phytother Res. 2020 Apr;34(4):729-741. doi: 10.1002/ptr.6573. Epub 2019 Dec 11. Phytother Res. 2020. PMID: 31825145 Review.
Beneficial therapeutic effects of phenolic acids have been proven in various research projects including in vivo and in vitro studies. Gentisic acid (GA) is a phenolic acid that has been associated with useful effects on human health, such as antiinflammatory, antig …
Beneficial therapeutic effects of phenolic acids have been proven in various research projects including in vivo and in vitro studies. Ge …
Gentisic Acid Stimulates Keratinocyte Proliferation through ERK1/2 Phosphorylation.
Kim M, Kim J, Shin YK, Kim KY. Kim M, et al. Int J Med Sci. 2020 Feb 24;17(5):626-631. doi: 10.7150/ijms.36484. eCollection 2020. Int J Med Sci. 2020. PMID: 32210712 Free PMC article.
Gentisic acid improved HaCaT cell proliferation by over 20% in MTT assay. ...Thus, our study indicates that gentisic acid promotes the proliferation of keratinocyte by phosphorylation of ERK1/2....
Gentisic acid improved HaCaT cell proliferation by over 20% in MTT assay. ...Thus, our study indicates that gentisic …
Gentisic acid ameliorates type 2 diabetes induced by Nicotinamide-Streptozotocin in male mice by attenuating pancreatic oxidative stress and inflammation through modulation of Nrf2 and NF-B pathways.
Razliqi RN, Ahangarpour A, Mard SA, Khorsandi L. Razliqi RN, et al. Life Sci. 2023 Jul 15;325:121770. doi: 10.1016/j.lfs.2023.121770. Epub 2023 May 14. Life Sci. 2023. PMID: 37192699
AIMS: There is a close link between oxidative stress, inflammation, and type 2 diabetes mellitus (T2DM). Gentisic acid (GA) is a di-phenolic compound and an active metabolite of aspirin that possesses antioxidant and anti-inflammatory properties, but its potential a …
AIMS: There is a close link between oxidative stress, inflammation, and type 2 diabetes mellitus (T2DM). Gentisic acid (GA) is …
Gentisic acid prevents the transition from pressure overload-induced cardiac hypertrophy to heart failure.
Sun S, Kee HJ, Ryu Y, Choi SY, Kim GR, Kim HS, Kee SJ, Jeong MH. Sun S, et al. Sci Rep. 2019 Feb 28;9(1):3018. doi: 10.1038/s41598-019-39423-8. Sci Rep. 2019. PMID: 30816171 Free PMC article.
Here, we examined whether gentisic acid prevents the development of heart failure. Heart failure was induced in mice via chronic TAC. ...After oral administration of gentisic acid (2000 mgkg(-1)), no significant differences in organ weight, histology, …
Here, we examined whether gentisic acid prevents the development of heart failure. Heart failure was induced in mice via chron …
Gentisic acid ameliorates cisplatin-induced reprotoxicity through suppressing endoplasmic reticulum stress and upregulating Nrf2 pathway.
Mentese A, Demir S, Mungan SA, Alemdar NT, Demir EA, Aliyazicioglu Y. Mentese A, et al. Tissue Cell. 2023 Dec;85:102256. doi: 10.1016/j.tice.2023.102256. Epub 2023 Oct 24. Tissue Cell. 2023. PMID: 37918215
Reproductive toxicity is a serious side effect of cisplatin (CP) chemotherapy. Gentisic acid (GTA) is a phenolic acid with strong antioxidant properties. ...
Reproductive toxicity is a serious side effect of cisplatin (CP) chemotherapy. Gentisic acid (GTA) is a phenolic acid with str …
Homogentisic Acid and Gentisic Acid Biosynthesized Pyomelanin Mimics: Structural Characterization and Antioxidant Activity.
Al Khatib M, Costa J, Spinelli D, Capecchi E, Saladino R, Baratto MC, Pogni R. Al Khatib M, et al. Int J Mol Sci. 2021 Feb 9;22(4):1739. doi: 10.3390/ijms22041739. Int J Mol Sci. 2021. PMID: 33572316 Free PMC article.
Pyomelanin mimics from homogentisic acid (HGA) and gentisic acid (GA) were biosynthesized by the oxidative enzyme T. versicolor laccase at physiological pH to obtain water soluble melanins. ...
Pyomelanin mimics from homogentisic acid (HGA) and gentisic acid (GA) were biosynthesized by the oxidative enzyme T. versicolo …
Gentisic acid attenuates pressure overload-induced cardiac hypertrophy and fibrosis in mice through inhibition of the ERK1/2 pathway.
Sun S, Kee HJ, Jin L, Ryu Y, Choi SY, Kim GR, Jeong MH. Sun S, et al. J Cell Mol Med. 2018 Dec;22(12):5964-5977. doi: 10.1111/jcmm.13869. Epub 2018 Sep 6. J Cell Mol Med. 2018. PMID: 30256522 Free PMC article.
We previously reported that gentisic acid (2,5-dihydroxybenzoic acid) is the third most abundant phenolic component of Dendropanax morbifera branch extracts. ...Beginning 2 weeks after this procedure, the mice were given daily intraperito …
We previously reported that gentisic acid (2,5-dihydroxybenzoic acid) is the third most abundant p …
Insight into Gentisic Acid Antidiabetic Potential Using In Vitro and In Silico Approaches.
Mechchate H, Es-Safi I, Mohamed Al Kamaly O, Bousta D. Mechchate H, et al. Molecules. 2021 Mar 30;26(7):1932. doi: 10.3390/molecules26071932. Molecules. 2021. PMID: 33808152 Free PMC article.
Numerous scientific studies have confirmed the beneficial therapeutic effects of phenolic acids. Among them gentisic acid (GA), a phenolic acid extensively found in many fruit and vegetables has been associated with an enormous confirmed health benefit. The present …
Numerous scientific studies have confirmed the beneficial therapeutic effects of phenolic acids. Among them gentisic acid (GA) …
1,431 results